痘痘的藥
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內容
JOJO
請教醫生 為什麼痘痘的藥前兩天要吃類固醇呢?這樣痘痘不是會更惡化嗎?那吃嘞有何效用呢
(IP:218.165.114.145)     日期: 2007-01-10 22:14:50
Brian
[回覆給:]
我隨便上網找一篇國外論文。請看以下英文部分。
青春痘(acne)
類固醇(prednisolone)可以治療青春痘。
但是每天長期使用類固醇反而會導致青春痘。

所以按照王院長指示方式使用類固醇,可以治好青春痘又可以避免副作用。

可是國內媒體與部份醫師把類固醇妖魔化。
甚至拿來打擊同業醫師。這就是台灣亂象,不願意告知消費者學理,鼓勵斷章取義。

建議可以適度使用類固醇,但是請勿濫用,就不會有副作用。
節錄以下論文的一句話:
was successfully treated initially with prednisolone
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Titre du document / Document title
Severe vulval apocrine acne successfully treated with prednisolone and isotretinoin
Auteur(s) / Author(s)
FEARFIELD L. A. (1) ; STAUGHTON R. C. D. (1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Department of Dermatology, Chelsea and Westminster Hospital, Imperial College School of Medicine, London, ROYAUME-UNI

Résumé / Abstract
Apocrine acne, otherwise known as hidradenitis suppurativa, is a chronic inflammatory scarring disease affecting the apocrine gland-bearing skin. We present a case of a 34-year-old woman with severe vulval apocrine acne who was successfully treated initially with prednisolone and then maintained on long-term isotretinoin. This case indicates that long-term treatment with isotretinoin may be more successful than the usual 4-6 months treatment regime.
(IP:218.165.101.6)     日期:  2007-01-10 22:54:00
[回覆給:]
使用類固醇治療青春痘的論文很多
隨便到國外網站都找得到。

Abstract

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British Journal of Dermatology
Volume 141 Issue 2 Page 307 - August 1999
doi:10.1046/j.1365-2133.1999.02982.x
Volume 141 Issue 2


The treatment of acne fulminans: a review of 25 cases
Seukeran & Cunliffe
The treatment of acne fulminans has been difficult. It is difficult to perform a controlled treatment trial due to the rarity of the complication. However, it is possible to compare four different therapeutic regimens which have evolved with time in the management of 25 patients over a period of 25 years. Oral antibiotics produced a slow response in the resolution of acne and systemic symptoms. The addition of a systemic steroid produced a quick resolution of systemic features, but the time until resolution of the acne was longer than when it was used in combination with oral isotretinoin. The protocols which used a combination of prednisolone and isotretinoin led to faster control of systemic features as well as clearance of acne when compared with other protocols. This was particularly so if the oral steroid was used sooner rather than later. We conclude that the preferred treatment of acne fulminans is oral prednisolone 0.5–1 mg/kg daily for 4–6 weeks (thereafter slowly reduced to zero) with oral isotretinoin being added to the regimen at the fourth week, initially at 0.5 mg/kg daily and gradually increased to achieve complete clearance.

(IP:218.165.101.6)     日期: 2007-01-10 22:57:00